Paraneoplastic neurological disorders
نویسنده
چکیده
M. COJOCARU, MD, PhDa; Inimioara Mihaela COJOCARU, MD, PhDb; Isabela SILOSI, MD, PhDc aPhysiology Department, Faculty of Medicine, ”Titu Maiorescu” University, Bucharest, Romania bNeurology Clinic, “Carol Davila” University of Medicine and Pharmacy, “Colentina” Clinical Hospital, Bucharest, Romania cImmunology Department, Faculty of Medicine and Pharmacy, Craiova, Romania EDITORIALS Mædica a Journal of Clinical Medicine
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Ma1, a novel neuron- and testis-specific protein, is recognized by the serum of patients with paraneoplastic neurological disorders.
The identification of antineuronal antibodies has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated tumours. It has also led to the cloning of possibly important neuron-specific proteins. In this study we wanted to identify novel antineuronal antibodies in the sera of patients with paraneoplastic neurological disorders and to clone the ...
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OBJECTIVE Paraneoplastic neurological syndromes (PNS) were initially defined as neurological syndromes with unknown etiology that often associate with cancer. This broad definition may lead to misconception that any neurological syndrome, which coincides with a cancer might be considered as PNS. In the last two decades it has been suggested that PNSs are mainly immune-mediated. The detection of...
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Introduction: Paraneoplastic neurological syndrome is a rare complication of different types of cancer. Non-small cell neuro-endocrine lung cancer is very rare and there are few descriptions of paraneoplastic syndrome in patients with such types of cancer. Paraneoplastic movement disorders, among them chorea, have an exceptionally rare occurrence. Clinical presentation: A 64-year-old woman pres...
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Paraneoplastic neurological syndromes are uncommon, however; their diagnosis is of major practical importance. Any portion of the nervous system may be involved in paraneoplastic syndromes. There is increasing evidence that the pathogenesis of many paraneoplastic neurological syndromes appears to be an immune reaction against antigen shared by the cancer and the nervous system. The identificati...
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The incidence of paraneoplastic syndromes in animals is not known. Best descriptions oxford a z of grammar and punctuation pdf free download of paraneoplastic syndromes exist for the dog. Recognition.Recent medical advances have improved the understanding, diagnosis, and treatment of paraneoplastic syndromes. These disorders arise from tumor secretion.Paraneoplastic syndromes are frequently fou...
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Paraneoplastic neurological syndromes (PNS) are remote effects of cancer that are not caused by invasion of the tumor or its metastases. Immunologic factors appear important in the pathogenesis of PNS because antineuronal autoantibodies and T-cell responses against nervous system antigens have been defined for many of these disorders. The immunologic response is elicited by the ectopic expressi...
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